PeptulatorReconstitution and dosing maths

Retatrutide dosing chart

Every dose from 1 to 12 mg in units, for 10, 20 and 30 mg vials at three water volumes, and the four-week ladder with how many vials it eats.

Retatrutide is an investigational triple agonist, not an approved medicine, and vials sold online are research material. Reported protocols start at 1 or 2 mg once a week and step up every four weeks. This chart converts every step from 1 to 12 mg into insulin syringe units for the common vial sizes and water volumes.

10 mg vial

WaterConc.1 mg2 mg3 mg4 mg5 mg6 mg8 mg10 mg12 mg
1 mL10 mg/mL10203040506080100-
2 mL5 mg/mL20406080100120*160*200*-
3 mL3.33 mg/mL306090120*150*180*240*300*-

20 mg vial

WaterConc.1 mg2 mg3 mg4 mg5 mg6 mg8 mg10 mg12 mg
1 mL20 mg/mL51015202530405060
2 mL10 mg/mL10203040506080100120*
3 mL6.67 mg/mL153045607590120*150*180*

30 mg vial

WaterConc.1 mg2 mg3 mg4 mg5 mg6 mg8 mg10 mg12 mg
1 mL30 mg/mL3.36.71013.316.72026.733.340
2 mL15 mg/mL6.713.32026.733.34053.366.780
3 mL10 mg/mL10203040506080100120*

Units on a standard U-100 insulin syringe. * means more than 100 units, so more than one 1 mL syringe. A dash means the dose is larger than the vial.

The reported ladder, with vial counts

StageWeeksDoseUnits (10 mg in 2 mL)Vials used so far (10 mg)
Stage 1weeks 1 to 42 mg weekly40 units0.8
Stage 2weeks 5 to 84 mg weekly80 units2.4
Stage 3weeks 9 to 126 mg weekly120 units4.8
Stage 4weeks 13 to 168 mg weekly160 units8
Stage 5weeks 17 to 2010 mg weekly200 units12
Stage 6weeks 21 to 2412 mg weekly240 units16.8

Stepping every four weeks from 2 to 12 mg takes 24 weeks and 16.8 vials of 10 mg, most of it in the last two stages. That is the case for buying 20 or 30 mg vials once you are past 6 mg. Many people never go that high; the trials that reported the largest weight loss used 8 and 12 mg, and the right ceiling is a clinical question.

Retatrutide dosing chart: 1 to 12 mg converted to insulin syringe units at 2.5, 5, 10 and 15 mg/mL
Retatrutide dosing chart. Save or print this one, or download the full-size image. Open the live calculator to use your own numbers.
Live version: the retatrutide dosage calculator, and the titration schedule for your own vial and water.

Peptulator, peptulator.com. Research use only, not medical advice.

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Common questions

How many units is 2 mg of retatrutide?
In a 10 mg vial with 2 mL of water, 40 units. With 1 mL, 20 units. In a 20 mg vial with 2 mL, 20 units. The concentration decides it.
What is the retatrutide dosing schedule?
Reports describe starting at 1 or 2 mg once a week and stepping up by 2 mg every four weeks, commonly stopping somewhere between 4 and 12 mg. There is no licensed schedule; it is an investigational compound.
How many vials does a full retatrutide ladder use?
From 2 to 12 mg in 2 mg steps every four weeks: 168 mg over 24 weeks, which is 16.8 vials of 10 mg, 8.4 of 20 mg or 5.6 of 30 mg.

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Tools

Before you use these numbers This is a unit-conversion tool. It turns a vial strength and a water volume into a concentration, a draw volume and a syringe mark. It does not tell you what to take, whether to take it, or whether a compound is safe for you. Most compounds listed are sold for laboratory research and are not approved for human use. Nothing here is medical advice. Dosing decisions belong with a licensed clinician who knows your history. Always check the strength printed on your own vial rather than trusting a preset.