PeptulatorReconstitution and dosing maths

Melanotan II dosage calculator

Melanotan II is dosed in micrograms from a 10 mg vial. The small starting doses land low on the barrel, so the water volume matters.

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Dose to units at the usual vial and water

DoseU-100 unitsDrawDoses per vialVial lasts
100 mcg2 units0.02 mL100100 days
250 mcg5 units0.05 mL4040 days
500 mcg10 units0.1 mL2020 days
750 mcg15 units0.15 mL1313 days
1000 mcg20 units0.2 mL1010 days

10 mg vial in 2 mL of bacteriostatic water (5 mg/mL), U-100 insulin syringe, once daily.

About Melanotan II

Melanotan II is a synthetic analogue of alpha-MSH that darkens skin by stimulating melanin. It is not approved anywhere, has been the subject of regulator warnings, and is sold for research. Nausea, flushing and new or darkening moles are the most reported effects.

Reports describe starting at 100 to 250 mcg to test tolerance, rising over days to 500 mcg or so, then dropping to occasional maintenance doses. A 10 mg vial with 2 mL of water is 5,000 mcg/mL, so 250 mcg is 0.05 mL, or 5 units. That is a small draw; 3 mL of water makes it 7.5 units. Melanotan I (afamelanotide) is a different, longer-acting compound with its own dosing.

The same 10 mg vial at other water volumes

If the draw is awkward to read, change the water, not the dose. The dose stays the same; only the mark moves.

VialBAC waterConcentrationDrawU-100 unitsDoses/vial
10 mg1 mL10 mg/mL0.025 mL2.5 units40
10 mg2 mL5 mg/mL0.05 mL5 units40
10 mg3 mL3.33 mg/mL0.075 mL7.5 units40

All rows above assume a 250 mcg dose and a standard U-100 insulin syringe, where 100 units = 1 mL.

How long it lasts in the body

Not well characterised in humans. A decay curve is only drawn where a human half-life is documented, so there is none here. Treat any precise figure for Melanotan II elsewhere with caution.

Common questions

How many units is 250 mcg of Melanotan II?
It depends entirely on how much water you added. In a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so 250 mcg is 0.05 mL, which is 5 units on a U-100 insulin syringe. In the same vial with 1 mL of water it is 2.5 units, and with 3 mL it is 7.5 units.
How much bacteriostatic water for a 10 mg Melanotan II vial?
2 mL is the usual choice. It gives 5 mg/mL, which puts the commonly reported range of 100 mcg to 1000 mcg between roughly 2 and 20 units. Aim for a draw between about 10 and 50 units, where the barrel is easiest to read, and add or remove water to get there.
How many doses are in a 10 mg vial?
Divide 10 by your dose. At 250 mcg that is 40 doses, which at once daily is 40 days.
How many units is 250 mcg of Melanotan II?
In a 10 mg vial with 2 mL of water, 5 units on a U-100 syringe. With 1 mL of water it is 2.5 units, which is hard to read accurately.
IndependentThis site does not sell peptides and is not owned by a vendor.
The maths is openThe formula is on every page and in the methodology. The code is one file with an automated test suite, run before each deploy.
How it earnsAffiliate links on one marked page, never inside the calculator.
ReviewedDose ranges and half-lives checked 3 September 2026.

Buying Melanotan II?

The where to buy page lists the vendors this site uses and what to check first. Peptide Bureau keeps the ranked scorecard.

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Tools

Before you use these numbers This is a unit-conversion tool. It turns a vial strength and a water volume into a concentration, a draw volume and a syringe mark. It does not tell you what to take, whether to take it, or whether a compound is safe for you. Most compounds listed are sold for laboratory research and are not approved for human use. Nothing here is medical advice. Dosing decisions belong with a licensed clinician who knows your history. Always check the strength printed on your own vial rather than trusting a preset.